Bayesian Network Studies for Splicing Regulatory Elements Bayesian Network Studies for Splicing Regulatory Elements. Introduction
نویسندگان
چکیده
Estudi de xarxes bayesianes per a elements de regulació de splicing.
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متن کاملIntroduction to Splicing
Splicing is the process by which introns are removed from an mRNA precursor (pre-mRNA) and exons are ligated to form a mature mRNA 1. Most types of splicing, in organisms ranging from yeast to human, take place within the spliceosome�a large complex comprised of five ribonucleoproteins (RNPs) containing the small nuclear RNAs (snRNAs) U1, U2, U4, U5, and U6 and a...
متن کاملIntroduction to Splicing
Splicing is the process by which introns are removed from an mRNA precursor (pre-mRNA) and exons are ligated to form a mature mRNA 1. Most types of splicing, in organisms ranging from yeast to human, take place within the spliceosome�a large complex comprised of five ribonucleoproteins (RNPs) containing the small nuclear RNAs (snRNAs) U1, U2, U4, U5, and U6 and a...
متن کاملCoevolutionary networks of splicing cis-regulatory elements.
Accurate and efficient splicing of eukaryotic pre-mRNAs requires recognition by trans-acting factors of a complex array of cis-acting RNA elements. Here, we developed a generalized Bayesian network to model the coevolution of splicing cis elements in diverse eukaryotic taxa. Cross-exon but not cross-intron compensatory interactions between the 5' splice site (5'ss) and 3' splice site (3'ss) wer...
متن کاملIntroduction to Splicing
Splicing is the process by which introns are removed from an mRNA precursor (pre-mRNA) and exons are ligated to form a mature mRNA 1. Most types of splicing, in organisms ranging from yeast to human, take place within the spliceosome�a large complex comprised of five ribonucleoproteins (RNPs) containing the small nuclear RNAs (snRNAs) U1, U2, U4, U5, and U6 and a...
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تاریخ انتشار 2008